So what is NAD+?
NAD+ is an important co-enzyme in your cells that plays a critical role in metabolism and energy production.
Our metabolism wouldn’t fuction without it and our cells would die if we did not have NAD+. This has been understood for many decades.
More recently, however is the work in which Dr. Charles Brenner learned the pathways in which NAD+ repairs DNA in cells when they become damaged by oxidants such as ultraviolet light.
NAD+ Declines as We Age
One reason why we look and feel older as we age chronologically is that we have a reduction in the concentration of NAD+ in our bodies. With less NAD+, our cells are less energetic which contributes to a number of declining processes within all of us.
Slower cell turnover – slower turnover means dull looking skin
Lower capability to repair cells – as our skin cells are damaged by UV light and other oxidants, they lose the ability to repair themselves which means more wrinkles and dark spots
Lower collagen synthesis – with reduced ability to synthesize collagen, our skin becomes less firm, more wrinkles form and skin sags
Higher inflammatory responses – with a reduced ability to mediate inflammatory responses we commonly see more redness.
How can we address these concerns at the cellular level?
NR can replenish NAD+
Nicotinamide Riboside, or NR, is a Precursor of NAD+ Energy Metabolism.
And NR can replenish NAD+ and combat the declining cellular energy production associated with age.
So what does this mean in terms of skincare? NR can boost collagen production, smooth skin, and reduce the appearance of wrinkles!
How do we know this?
Dr. Charles Brenner is the world’s foremost authority on NAD+. He discovered the Nicotinamide Riboside mechanism and pathway to becoming NAD+.
Dr. Brenner holds 2 seminal patents related to NR, and he happens to be one of our co-founders and Chief Scientific Advisor.
The first intracellular skincare ingredient
Nicotinamide Riboside (NR) is the first intracellular skincare ingredient. NR has a transport mechanism that allows it to pass through the cell membrane.
Only NR can only enhance NAD+ levels within the cell, while other NAD-related ingredients, such as NMN and pure NAD+ must go through biochemical processes to become NR.
Clinical Trials Validated Anti-Aging Benefits
The company conducted clinical trials on Ayucell products, and they validated our anti-aging benefits. In the US, companies can typically call products ‘Anti-Aging’ without any real scientific support or proof on the finished product, however in Korea there is certain criteria that must be met to be called an Anti-Aging product – that includes clinical trials.
Ayucell conducted clinical trials by an independent lab, followed specific test protocols, and measured both qualitatively and quantitatively. Our products had 2 independent studies - one for Serum and one for Cream. The results were impressive!
You can read about each clinical trial and the impressive results on the individual product detail page, however the top result is too good to not share. The average age index reduction was 10 weeks in 8 weeks of use (twice per day)!